Mechanisms of renal damage in mixed cryoglobulinaemia nephritis
نویسندگان
چکیده
منابع مشابه
Bone marrow B-cell clonal expansion in type II mixed cryoglobulinaemia: association with nephritis.
OBJECTIVES To investigate the relationship between the pattern of bone marrow (BM) B-cell expansion and the clinical features of mixed cryoglobulinaemia (MC) syndrome. METHODS Fifty-five patients with type II MC syndrome were analysed. Their median age was 64 yrs (range 24-82), the median disease duration was 6 yrs (range 1-26) and the mean follow-up after BM analysis was 2.65 yrs (s.d. = 1.3...
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The prevalence of various forms of peripheral neuropathy has not been previously assessed in large series of patients with essential mixed cryoglobulinaemia (EMC). Clinical and electrophysiological signs of peripheral neuropathy were observed in 21 of 37 EMC patients, consisting of polyneuropathy in 19, mononeuropathy or multiple mononeuropathy in eight, and both in six. The various forms of pe...
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Primary mixed cryoglobulinaemia was diagnosed in a 65-year-old woman and confirmed on post-mortem examination. The patient had the classical findings of purpura, arthralgia, renal failure, mixed cryoglobulins in the serum and rheumatoid factor activity. The patient presented with haemolytic anaemia and later developed rectal bleeding, but the most prominent feature was an acute psychosis with e...
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renal vasculitis of small and medium-size vessels are Introduction frequent. In less severe cases, a mesangial lesion may be seen [2]. Mixed cryoglobulinaemia (MC) is a rare systemic disease characterized by circulating cold precipitable mixed immunoglobulins composed of monoclonal IgM rheumTreatment of MC nephritis atoid factor and polyclonal IgG. Purpura, weakness, arthralgias and glomerulone...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2001
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/16.suppl_6.58